News & Publications
News
Aposense Receives Grant for Expanding its Molecular-Nano-Motors (MNMs) Delivery Platform to mRNA
Grant from Bill & Melinda Gates Foundation will support Development of Groundbreaking Macromolecule Drug Delivery Platform
SirVir obtains positive results in pre-clinical experiment against COVID-19
The English translation of an interview on Ynet with Prof. Roger Kornberg the scientific president of Aposense and SirVir. Petach Tikva, and Ness-Ziona, Israel. (April
Aposense enters into an out-licensing agreement with Processa Pharmaceuticals
Aposense announces that it entered into a license agreement with Processa Pharmaceuticals to license out its anti-cancer pro drug the ATT-11TA. PETACH TIKVA – June1,
Publication
Damianovich, M., Ziv, I., Heyman, S. N., Rosen, S., Shina, A., Kidron, D., Aloya, T., Grimberg, H., Levin, G., Reshef, A., Bentolila, A., Cohen, A., & Shirvan, A. (2005). ApoSense: a novel technology for functional molecular imaging of cell death in models of acute renal tubular necrosis. European Journal of Nuclear Medicine and Molecular Imaging, 33(3), 281–291.
Reshef, A., Shirvan, A., Waterhouse, R. N., Grimberg, H., Levin, G., Cohen, A., Ulysse, L. G., Friedman, G., Antoni, G., & Ziv, I. (2008). Molecular Imaging of Neurovascular Cell Death in Experimental Cerebral Stroke by PET. Journal of Nuclear Medicine, 49(9), 1520–1528.
Grimberg, H., Levin, G., Shirvan, A., Cohen, A., Yogev-Falach, M., Reshef, A., & Ziv, I. (2009). Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis. Apoptosis, 14(3), 257–267.
Cohen, A., Shirvan, A., Levin, G., Grimberg, H., Reshef, A., & Ziv, I. (2009). From the Gla domain to a novel small-molecule detector of apoptosis. Cell Research, 19(5), 625–637.
Höglund, J., Shirvan, A., Antoni, G., Gustavsson, S. K., Långström, B., Ringheim, A., Sörensen, J., Ben-Ami, M., & Ziv, I. (2011). 18F-ML-10, a PET Tracer for Apoptosis: First Human Study. Journal of Nuclear Medicine, 52(5), 720–725.
Allen, A. M., Ben-Ami, M., Reshef, A., Steinmetz, A., Kundel, Y., Inbar, E., Djaldetti, R., Davidson, T., Fenig, E., & Ziv, I. (2012). Assessment of response of brain metastases to radiotherapy by PET imaging of apoptosis with 18F-ML-10. European Journal of Nuclear Medicine and Molecular Imaging, 39(9), 1400–1408.
Grimberg, H., Van-Gelder, J., Ziv, I. (2022). ATT-11T – A novel based SN-38 pro-drug A Direct Arrow to the Target Tumor Tissue. Manuscript in Preparation.
Ziv, I., Grimberg, H., Harel, L., Van Gelder, J. M., Kornberg, G. L., Kornberg, R. D., Ziv, I. (2022). A novel and efficient siRNA delivery modality by harnessing of the internal cell membrane electric field. Manuscript in Preparation.
Grimberg, H., Harel, L., Sattler, R. A., Mantlo, E. K., Van Gelder, J. M., Kornberg, G. L., Paessler, S., Kornberg, R. D., Ziv, I. (2022). Novel siRNA delivery mechanism allows for potent prophylactic protection against SARS-CoV-2 in non-human primates. Manuscript in Preparation.